- Summarize the role of the neonatal Fc receptor (FcRn) in IgG homeostasis.
- Discuss how dysregulation of the alternative complement pathway leads to paroxysmal nocturnal hemoglobinuria (PNH).
- Identify features of clonal hematopoiesis of indeterminate potential (CHIP) that confer high risk of progression to a myeloid neoplasm.
- Outline key gene therapies currently in trials for sickle cell disease and beta thalassemia
- Discuss updates in anticoagulation for specific indications
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