PANDAS and PANS: The Controversy

Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus (PANDAS) and Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) are clinical syndromes occurring in children which are characterized by the abrupt onset of neurobehavioral symptoms (most often obsessive-compulsive disorder). PANS is the umbrella term for the disorder. When the instigating event is group A streptococcus, the syndrome is referred to as PANDAS. The biologic plausibility for these disorders is provided by the example of acute rheumatic fever which is precipitated by a throat infection with Group A streptococcus. This activity discusses acute rheumatic fever and Sydenham chorea as a model for PANDAS and PANS and reviews the diagnostic criteria and approach to management of these entities.

Intended Audience

Pediatric providers, including physicians, nurses, physician assistants, and other providers interested in learning more about PANDAS and PANS clinical syndromes.

Learning Objectives

As a result of participating in this activity, learners, as members of the healthcare team, will be able to: 

  • Discuss the clinical spectrum and criteria for the diagnosis of neurobehavioral syndromes, PANDAS and PANS
  • Review streptococcal pharyngitis and acute rheumatic fever with concentration on the major manifestation of chorea, for plausibility of PANDAS
  • Review the original description of PANDAS and a typical case, and highlight controversial issues that have resulted in skepticism
  • Discuss the newer concept of PANS and approach to diagnosis and management
Course summary
Available credit: 
  • 0.50 AMA PRA Category 1 Credit™
  • 0.50 University of Wisconsin–Madison Continuing Education Hours
    • 0.50 Approved for AMA PRA Category 1 Credit™
Registration opens: 
08/29/2024
Course expires: 
08/28/2026
Cost:
$0.00
Rating: 
0

Ellen Wald, MD
Professor, Department of Pediatrics, Division of Infectious Diseases
University of Wisconsin School of Medicine and Public Health

Gregory DeMuri, MD
Professor, Department of Pediatrics, Division of Infectious Diseases
University of Wisconsin School of Medicine and Public Health

Faculty Disclosure

It is the policy of the University of Wisconsin–Madison Interprofessional Continuing Education Partnership (ICEP) to identify, mitigate and disclose all relevant financial relationships with ineligible companies* held by the  speakers/presenters, authors, planners, and other persons who may influence content of this accredited continuing education (CE).  In addition, speakers, presenters and authors must disclose any planned discussion of unlabeled/unapproved uses of drugs or devices during their presentation.

* Ineligible companies are those whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on, patients. The ACCME does not consider providers of clinical services directly to patients to be ineligible companies.

For this accredited continuing educational activity all relevant financial relationships have been mitigated and detailed disclosures are listed below:

Name

Role

Financial Relationship Disclosures

Discussion of Unlabeled/Unapproved uses of drugs/devices in presentation?

Ellen Wald, MD

Course Director, Medical Director, Speaker/Author, Planner

AstraZeneca (Contractor)

No

Gregory DeMuri, MD

Reviewer, Planner

No relevant relationships with ineligible companies to disclose

No

Discloser List CME Internal Report

Accreditation Statement

imageIn support of improving patient care, the University of Wisconsin–Madison ICEP is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Credit Designation Statements

American Medical Association (AMA)

The University of Wisconsin–Madison ICEP designates this live activity for a maximum of 0.5 AMA PRA Category 1 Credits™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Continuing Education Units

The University of Wisconsin–Madison, as a member of the University Continuing Education Association (UCEA) authorizes this program for 0.5 continuing education units (CEUs) or 0.05 hours.  

Available Credit

  • 0.50 AMA PRA Category 1 Credit™
  • 0.50 University of Wisconsin–Madison Continuing Education Hours
    • 0.50 Approved for AMA PRA Category 1 Credit™

Cost:
$0.00
Please login or register to take this course.

Registration for this activity can only be completed through the ICEP Learning Portal. Attendee registrations made through any other sites cannot be honored. UW-Madison ICEP is not able to refund fees paid through unaffiliated registration sites, such as eMedEvents.com, MedConfWorld.com, EventEgg.com, and 10times.com. Please report any unauthorized websites or solicitations for registrations to [email protected].

Accessibility

The University of Wisconsin provides equal opportunities in employment and programming, including Title IX requirements. The University of Wisconsin fully complies with the legal requirements of the ADA and the rules and regulations thereof. If any participant in this educational activity is in need of accommodations, please notify us at [email protected]

Questions? 

[email protected]

Required Hardware/software

Computer, tablet, or other mobile device with sound.
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