Randomized Trials and Their Independent Data Monitoring Committees: Impacts on Clinical Practice
This conference has been designed to help physicians incorporate and appreciate the following within their clinical practice:
- Make more astute clinical judgments based on the totality of evidence which should include the data from large-scale randomized trials of interventions;
- The unique role of large-scale randomized trials in detecting small to moderate effects of interventions; and
- The unique and crucial contribution of Independent Data Monitoring Committees to patient safety and trial integrity.
Along with content experts, learners will explore some of the most notable studies that were affected by the presence of Independent Data Monitoring Committees (DMCs). Learners will also explore the unique role DMCs play in clinical practice.
This activity is designed for physicians (MD/DO), Advance Practice Providers (PA/NP/APRN), and pharmacists who serve on or will serve on Data Monitoring Committees, utilize, or hope to better utilize, clinical trial data in their practice.
Following the completion of this activity, learners will be able to:
1. Adapt their clinical judgements based on the totality of evidence without undue reliance on any guidelines in clinical decision making
2. Describe the crucial role randomized trials play in reliably detecting small to moderate benefits of interventions
3. Employ case-based learning to encourage the use of independent data monitoring committees in research
|Saturday, February 29, 2020|
|7:00 am - 7:30 am||Registration & Continental Breakfast|
|7:30 am - 7:45 am||Welcome (TBD)|
|7:45 am - 8 :00 am|
David L. DeMets, PhD
Paul M. Ridker, MD, MPH
|8:00 am - 8:45 am|
The Need for Randomized Trials in Concluding Statistical Association and Judging Causation and their Influence on Clinical Practice
Charles H. Hennekens, MD, DrPH
|8:45 am - 9:30 am|
The Evolution of Independent Data Monitoring Committees in the Conduct of Randomized Trials and their Influence on Clinical Practice
James Neaton, PhD
Paul M. Ridker, MD, MPH
|9:30 am - 10:00 am||Break|
|10:00 am - 12:30 pm|
Small Group Discussions of Case Studies: How Data Monitoring Committee Decisions in Randomized Trials Have Influenced Clinical Practice - Part I
|Sunday, March 1, 2020|
|7:00 am - 7:30 am||Registration and Breakfast|
|7:30 am - 8:15 am|
The Roles of Investigators, Sponsors, and Independent Data Monitoring Committees in Randomized Trials and their Relevance to Clinical Practice
Susan Ellenberg, PhD
Christopher B. Granger, MD, FACC
|8:15 am - 9:00 am|
Statistical Methods in Data Monitoring of Randomized Trials and their Impacts on Clinical Practice
David L. DeMets, PhD
Jean Rouleau, MD
|9:00 am - 10:15 am||Break|
|10:15 am - 12:30 pm||Small Group Discussions of Case Studies: How Data Monitoring Committee Decisions in Randomized Trials Have Influenced Clinical Practice - Part II|
A block of rooms has been reserved at the conference site, Boca Raton Club & Resort. Please use this website to book your accommodations: https://book.passkey.com/e/50013638https://book.passkey.com/e/50013638
It is the policy of the University of Wisconsin–Madison Interprofessional Continuing Education Partnership (ICEP) that the faculty, authors, planners, and other persons who may influence content of this continuing education (CE) activity disclose all relevant financial relationships with commercial interests* in order to allow CE staff to identify and resolve any potential conflicts of interest. Faculty must also disclose any planned discussion of unlabeled/unapproved uses of drugs or devices during their presentation(s). For this educational activity all conflicts of interest have been resolved and detailed disclosures are listed below.
*The ACCME defines a commercial interest as any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients. The ACCME does not consider providers of clinical service directly to patients to be commercial interests.
In support of improving patient care, this activity has been planned and implemented by the University of Wisconsin–Madison Interprofessional Continuing Education Partnership (ICEP) and Schmidt College of Medicine at Florida Atlantic University. The University of Wisconsin–Madison ICEP is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Credit Designation Statements
American Medical Association
The University of Wisconsin–Madison ICEP designates this live activity for a maximum of 8.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Accreditation Council for Pharmacy Education (ACPE)
The University of Wisconsin–Madison ICEP designates this live activity for a maximum of 8.5 or 8.5 CPE credits. Credit can be earned by documented attendance and by successfully completing the and evaluation. Credit will be provided to NABP CPE Monitor within 60 days after the activity completion.
Universal Activity Number (UAN): J0000358-XXXX-YR-XXX-L01-P
Continuing Education Units
The University of Wisconsin–Madison, as a member of the University Continuing Education Association (UCEA), authorizes this program for .85 continuing education units (CEUs) or 8.5 hours.
- 8.50 ACPE Contact Hours
- 8.50 AMA PRA Category 1 Credit™
- 0.85 University of Wisconsin–Madison Continuing Education Hours