Dr. Mary Clyde Pierce is a Professor of Emergency Medicine at the Northwestern University Feinberg School of Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago. 

After obtaining her MD from the Louisiana State University School of Medicine in 1989, Dr. Pierce completed her residency in Pediatrics at Johns Hopkins Hospital. Following residency, she completed a fellowship in Emergency Medicine at the University of Pittsburgh Medical Center. 

She joined faculty at Northwestern University Feinberg School of Medicine as a Professor of Pediatrics and Emergency Medicine. Dr. Pierce’s research interest focuses primarily on injuries in children with an emphasis on differentiating abusive from accidental trauma. Dr Pierce collaborates with a multi-disciplinary lab with emphasis on injury biomechanics. This lab combines the expertise of medicine and engineering and utilizes both a clinical and an experimental approach. Dr. Pierce’s research focus is the development of injury plausibility models, including clinical decision rules, for differentiating abusive and accidental trauma in the young child that combines medical, social, biologic, and engineering knowledge. Her interest is also in epigenetics, psychosocial risk factors, factors, ecologic factors, and how child maltreatment confers health problems later in life. This collaborative work results in translational research that is guided by case-based studies with clinical, social, and basic science research, experiments, and modeling directly linked to pertinent clinic issues.